Christina Applegate of Dead To Me has spoken up about how her Multiple Sclerosis (MS) diagnosis has affected her 14-year-old daughter, Sadie.

Applegate, 53, has always been brutally honest about how MS has impacted her life, describing it as the ‘worst thing she’s ever gone through.’

MS causes a breakdown of the protective coating of nerves, resulting in numbness, weakness, and difficulty walking, among other symptoms, and Applegate has been open about the ‘unimaginable’ anguish she has had as a consequence.

In the most recent episode of her podcast, Messy, Applegate revealed how the diagnosis has impacted more than just her, including her adolescent daughter.

Speaking to her co-host, Jamie-Lynn Sigler, the actor stated, “Sadie only knew me as healthy, a runner, a Pelotoner, and a dancer.”

When Applegate got her diagnosis in 2021, she characterized Sadie as being ‘stoic’ about the circumstance, but she has since realized that her daughter views her differently.

She continued, “I watch her glance at me when I’m in bed and can’t quite move, or when I want to go say good night to her in her room, but I can’t quite go down the corridor because my legs aren’t working that day.

“For example, at this moment, I can hardly go to the restroom.” It’s absolutely the worst. But that is neither here nor there. But… it broke her, and she had no idea. It seemed like she had lost her mother to this fucking creature. And I believe it is affecting her more as she has gotten older.

Sigler concurred, stating that MS is a ‘very hard reality’ for youngsters.

The Anchorman actor went on to add that her diagnosis occurred shortly after the COVID-19 outbreak, saying, “We had just gone through COVID, no school and all this stuff, and now Mommy can’t do all the things that she used to be able to do.”

“I can see it in her eyes. I see it,” she added. “But do you know what is truly beautiful?” She knows I’m having a difficult time since I’m anxious about being out. And she constantly has my arm.

“She’s always trying to assist me with my cane and whatnot. At home, she says, “Can you please go down and make my food because you’re the only one who can do it?” She says, ‘You’re going down all the steps.’ And I’m like, ‘Sadie, I can’t go down the fucking steps.’

But I do it. I do it because I know she is checking in to see whether she can still take care of me.