People believe the ‘Kennedy curse’ has struck one of America’s most prominent families.

The Kennedy family has long been regarded as America’s most renowned political dynasty, yet they have also experienced some unusual tragedies throughout the years.

From awful diseases to aircraft disasters, vehicle accidents, assassinations, and more, the family has endured grisly untimely deaths right out of a Final Destination film, prompting speculation of a ‘Kennedy curse.’

Even Ted Kennedy, the youngest of nine children of Joseph Patrick Kennedy and Rose Fitzgerald and JFK’s brother, wondered if ‘some dreadful curse did indeed linger over the Kennedys’ following a car accident and the unexplained deaths of four of his brothers by 1969.

Here are some of the occurrences that might be ascribed to the Kennedy ‘curse.’

Rosemary Kennedy, born in 1918, was believed to have been oxygen-deprived at birth and failed to reach developmental milestones throughout her life.

In 1941, when she was 23, her father decided to take her for an experimental new treatment called a lobotomy, which went horribly wrong.

Rosemary was left permanently disabled, with the mental capacity of a two-year-old.

She remained institutionalized for the majority of her life, unable to move or speak, until she died in January 2005 at the age of 86 years.

1944: Joe Kennedy, Jr.

When World War II broke out, Joe Kennedy, the eldest of the Kennedy siblings, had only just begun his political career.

So in June 1941, he joined the United States Naval Reserve.

However, on a top-secret bombing mission to Europe codenamed Anvil in August 1944, an explosive aboard his plane detonated prematurely, killing him and his co-pilot instantaneously.

Joe was just 29 years old when he died, and he was posthumously awarded the Navy Cross for his service.

1948: Kathleen Kennedy

Kathleen, sometimes known as Kick, had a number of personal traumas.

While working in the UK, she fell in love with Lord William Hartington, whom she married in May 1944, over her father’s desires.

Her brother, Joe, was the only family member to attend the wedding because he was stationed in Britain at the time.

We know Joe died three months after the nuptials, but Kathleen’s spouse also died shortly after.

Hartington was slain by a sniper while on active duty in Belgium, only four months after marrying.

Four years later, Kick died in an aircraft disaster in 1948.

1963: Patrick Kennedy

In August 1963, JFK’s wife, Jacqueline Kennedy, gave birth to a son, Patrick, whom they christened.

Unfortunately, the child only survived for 39 hours after being delivered prematurely and dying from complications of hyaline membrane illness.

JFK and Jacqueline had previously had a miscarriage and a stillbirth before Patrick’s death.

Three months after Patrick, John F. Kennedy was assassinated.

She was going to Paris to persuade her father to accept her new partner, the 8th Earl Fitzwilliam, who also died in the disaster.

1963: John F. Kennedy.

JFK spent the majority of his life suffering from chronic health ailments, as well as a lifelong back injury sustained while playing football as a boy.

While medically disqualified from the US Army in 1940, he enlisted in the US Naval Reserve, where he reinjured his back in a patrol torpedo boat accident in 1943 but bravely saved the life of another crewmember.

The most famous of the Kennedy tragedies occurred on November 22, 1963, when the then-president was slain in Dallas, Texas, at the age of 46.

1968: Robert F. Kennedy.

Robert Kennedy, the Kennedys’ seventh child, also joined politics in the 1960s, serving as attorney general from 1961 to 1964 before becoming a US senator representing New York.

In 1968, RFK emerged as a prominent candidate for the Democratic presidential nomination, intending to follow in his brother’s footsteps.

Tragically, not long after winning the California primary in June of that year, he was slain.

1969: Ted Kennedy

Edward ‘Ted’ Kennedy also participated in politics as a senator from 1962 until his death in 2009.

While dying of a brain tumor at the age of 77, two weeks after the death of his sister Eunice, the senator became involved in a tragedy in which he lived to tell the tale.

Ted left a party on Chappaquiddick Island late one evening in July 1969 to transport Mary Jo Kopechne, a partygoer, back to shore.

Ted apparently lost control of the automobile while driving, causing the duo to plunge into the sea.

Ted fled and swam to shore, finally reporting the event to police at 10 a.m. the next day, by which time the 28-year-old’s body had been discovered.

Ted was sentenced to two months of suspended jail time for fleeing the scene of an accident, as well as a 16-month driving suspension.

The so-called Chappaquiddick Incident harmed his reputation and his goal of becoming president.

1973: Ted Kennedy, Jr.

Ted’s son, named Edward Kennedy Jr., was born in 1961.

Ted Jr. was diagnosed with osteosarcoma, a kind of bone cancer, in his right leg when he was 12 years old.

In 1973, after numerous failed rounds of treatment, physicians decided to medically amputate his limb.

Though the 63-year-old is still alive and works as an attorney in New York City, it appears that the ‘Kennedy curse’ has accompanied him for most of his life.

Ted Jr. missed getting on Air Florida Flight 90 by 10 minutes, which crashed into the Potomac River and killed 74 people.

In 1984, David Kennedy, Robert F. Kennedy’s fourth son, born in 1955, nearly drowned.

His father leaped in to save his life. The following day, David witnessed his father’s assassination live on television.

According to reports, David turned to narcotics to cope with the stress, and a vehicle accident in 1973 led to his addiction to opioids.

He died in April 1984 of an overdose caused by a mix of cocaine and prescription medications.

1999: John Fitzgerald Kennedy, Jr.

On his third birthday, JFK Jr., popularly known as John-John, took part in his father’s burial procession.

As an adult, he worked for nearly four years as an assistant district attorney in Manhattan before becoming a writer and the publisher of George, a politics-lifestyle magazine.

After multiple high-profile romances with Hollywood’s most renowned faces, John-John married Carolyn Bessette in 1996.

Although the death of his cousin in a skiing accident delayed him for a few months, JFK Jr., a skilled pilot, opted to jet out with his wife and sister-in-law on July 16, 1999, to attend another cousin’s wedding.

The airplane failed to arrive, and days later, the wreckage of his plane was discovered strewn over the bottom.

All three corpses were retrieved.